What is Apolipoprotein B?
ApoB counts the number of harmful cholesterol particles in your blood. These are the particles that cause plaque buildup in your arteries. About 15-20% of people have high ApoB but normal cholesterol on a standard test. The 2026 AHA/ACC guidelines introduced ApoB targets alongside LDL and total cholesterol targets, reflecting growing evidence that ApoB is a more accurate predictor of heart disease risk.